Chromosome Aberration on Growth and Developmental Disorder

Growth and development in humans begin at conception, which shows progress interdependence. Normal children show the characteristic of growth development. In with disorder, chromosomal abnormality may be found. This study aimed to determine patients disorder. The samples were taken from karyotype results Medical Genetics Laboratory, Faculty Medicine, Universitas Wijaya Kusuma Surabaya, 2010-2020. inclusion criteria infants adolescents aged 24 years unmarried who experienced impaired development, including sexual Chromosomal abnormalities obtained cytogenetic analysis using G-banding method. From 75 disorders, there number autosomal chromosomes sex found Down syndrome, Turner Klinefelter Edwards syndrome. structural deletion, translocation, inversion, duplication, marker chromosome, heteromorphism. showed importance karyotyping developmental disorders.